Side-by-Side Comparison of Skin Biopsies and Skin Tape Stripping Highlights Abnormal Stratum Corneum in Atopic Dermatitis
نویسندگان
چکیده
منابع مشابه
Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy.
OBJECTIVE The aim of this study was to explore the tape strip sampling technique in the assessment of stratum corneum levels of inflammatory mediators in a clinical trial setting. METHODS Thirty-eight inflammatory mediators were analyzed by a multiplex-assay in the stratum corneum, collected by adhesive tapes before and after 6 weeks of therapy, in mild and moderate atopic dermatitis (AD) pat...
متن کاملSide to side comparison of topical treatment in atopic dermatitis.
OBJECTIVES To document and evaluate the outcome of side to side comparisons of different corticosteroids in determining the most effective topical treatment for individuals admitted to hospital for control of atopic dermatitis. METHODS Retrospective case note study of 82 admissions (66 children) to a children's hospital for treatment of atopic dermatitis between 1 June 1993 and 31 October 199...
متن کاملTape Stripping Technique for Stratum Corneum Protein Analysis
The aim of this study was to investigate the amount of protein in stratum corneum in atopic dermatitis (AD) patients and healthy controls, using tape stripping technique. Furthermore, to compare two different methods for protein assessment. Tape stripping was performed in AD patients and healthy controls to collect stratum corneum samples and subsequently analysed with two different methods: Sq...
متن کاملSolvent effects on the harvesting of stratum corneum from hairless mouse skin through adhesive tape stripping in vitro
125 pl of a propylene glycol/ethanol/water vehicle were applied for various lengths of time to 1.77 cm2 area of excised hairless mouse skin sections held in in vitro diffusion cells. After removal from the cell, each skin section was stripped repeatedly with a non-hygroscopic polypropylene tape. The amount of tissue removed in each strip was determined after allowing the volatile solvents to ev...
متن کاملSkin barrier function and stratum corneum hydration
Under normal circumstances, epidermis must be as impermeable as possible except for a small amount of water loss to hydrate the outer layers of the SC. Although all living cells require water to function, some “dead” cells also require water to be metabolically active. As it is the case of corneocytes, epidermis must retain sufficient water to (a) hydrate the outer layers of the SC to maintain ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.1160